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Pentylones is a novel stimulant-entactogen substance of the cathinone class.

it is chemically related to MDPV and belongs to a group known as the substituted cathinones.

Little is known about its pharmacology.

However it likely produces its activity by increasing the activity of serotonin,

dopamine, and norepinephrine in the brain.

the drug was developed in the 1960s by Boehringer Ingelheim, although it was never marketed.

It appeared around 2010 as recreational research compound,

it is occasionally found as an adulterant or counterfeit for MDMA.

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User reports indicate that it produces a mixture of classic stimulant and entactogenic effects resembling those of MDMA, methylone and cocaine.

Commonly reported effects include stimulation, disinhibition, increased libido,

compulsive redosing, and euphoria.

Very little is known about it at this time.

It is sold online as a research chemical alongside other synthetic cathinones like ethylone and dibutylone.

Due to the lack of research,

it is highly advised to use harm reduction practices if using this substance.

Appearance Of Pentylone

The hydrochloride salt of pentylone has been described as an off-white powder and a neat solid.

In its pure form, it is expected to be odorless and white.

Pharmacology Of Pentylone

The number of systematic studies available at this time is limited but it seems clear that it is a psychomotor stimulant.

In vitro, it has been demonstrated to block the reuptake of dopamine, norepinephrine and serotonin.

This was done using rat brain synaptosomal preparations with preference for the dopamine system.

Thus, its behaving cocaine- and MDPV-like rather than amphetamine-like.

Animal studies confirmed that it increases locomotor activity and that it substituted for methamphetamine and cocaine in drug discrimination studies.

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