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| Synonyms | benzodiazepine |
| IUPAC | 6-(2-chlorophenyl)-1-methyl-8-nitro-4H-s-triazolo(4,3-a)-(1,4)-benzodiazepine |
| PubChem | N/A |
| Cas# | N/A |
| Molecular Formula | C17H12ClN5O2 |
| Purity | 99% |
| Forumlation / Appearance | Pink/Purple Pellets and powder also |
only available as a research material and is not intended for human consumption.
reported to be highly potent, and concerns have been raised that clonazolam and flubromazolam in particular may pose comparatively higher risks than other designer benzodiazepines, due to their ability to produce strong sedation and amnesia at oral doses of as little as 0.5 mg.
Sample preparation and clonazolam results
Extraction of clonazolam was performed using liquid-liquid extraction method at an alkaline medium (Tris(hydroxymethyl)aminomethane buffer pH 9.0, mixed with acetonitrile and ethyl acetate). For the quantitative analysis of clonazolam, the blood sample internal standard (D5-oxazepam) was added [6]. A calibration curve for clonazolam (Cerilliant-Certified Reference Material) was prepared in the range of 0.01-0.2 mg/L. After 4 h, the concentration of clonazolam was 0.077 mg/L, then after 8 h, the
Discussion
Recently, designer benzodiazepines are rapidly increasing as drugs of abuse. However, they have never been applied in medical treatment, and limited data on its human acute toxicity and toxic levels in blood exist. Benzodiazepines, as a class of drugs are considered safe, but their toxicity is dose-dependent and they interact with alcohol and other drugs acting depressively on central nervous system [1]. The paper presents documented case report of clonazolam powder ingestion with coma and
